Publications
Publications
Adam Pawson has published extensively in peer-reviewed papers in top biomedical journals and is indexed in PubMed. You can also view all his publications on Googler Scholar and Web of Science.
83 Buneman P, Christie G, Davies JA, Dimitrellou R, Harding SD, Pawson AJ, Sharman JL, Wu Y. Why data citation isn't working, and what to do about it. Database (Oxford). 2020 Jan 1;2020:baaa022. doi: 10.1093/databa/baaa022. https://pubmed.ncbi.nlm.nih.gov/32367113
82 Alexander SPH, Armstrong JF, Davenport AP, Davies JA, Faccenda E, Harding SD, Levi-Schaffer F, Maguire JJ, Pawson AJ, Southan C, Spedding M. A rational roadmap for SARS-CoV-2/COVID-19 pharmacotherapeutic research and development: IUPHAR Review 29. Br J Pharmacol. 2020 May 1:10.1111/bph.15094. doi: 10.1111/bph.15094. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/32358833
81 Harding SD, Faccenda E, Southan C, Pawson AJ, Maffia P, Alexander SPH, Davenport AP, Fabbro D, Levi-Schaffer F, Spedding M, Davies JA. The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology. Immunology. 2020 Feb 5. doi: 10.1111/imm.13175. Epub 2020 Mar 2. Review. https://www.ncbi.nlm.nih.gov/pubmed/32020584
80 Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 2019 Dec;176 Suppl 1:S1-S20. doi: 10.1111/bph.14747. https://www.ncbi.nlm.nih.gov/pubmed/31710719
79 Alexander SPH, Cidlowski JA, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Nuclear hormone receptors. Br J Pharmacol. 2019 Dec;176 Suppl 1:S229-S246. doi: 10.1111/bph.14750. https://www.ncbi.nlm.nih.gov/pubmed/31710718
78 Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors. Br J Pharmacol. 2019 Dec;176 Suppl 1:S21-S141. doi: 10.1111/bph.14748. https://www.ncbi.nlm.nih.gov/pubmed/31710717
77 Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors. Br J Pharmacol. 2019 Dec;176 Suppl 1:S247-S296. doi: 10.1111/bph.14751. https://www.ncbi.nlm.nih.gov/pubmed/31710716
76 Alexander SPH, Mathie A, Peters JA, Veale EL, Striessnig J, Kelly E, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels. Br J Pharmacol. 2019 Dec;176 Suppl 1:S142-S228. doi: 10.1111/bph.14749. https://www.ncbi.nlm.nih.gov/pubmed/31710715
75 Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 2019 Dec;176 Suppl 1:S297-S396. doi: 10.1111/bph.14752. https://www.ncbi.nlm.nih.gov/pubmed/31710714
74 Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters. Br J Pharmacol. 2019 Dec;176 Suppl 1:S397-S493. doi: 10.1111/bph.14753. https://www.ncbi.nlm.nih.gov/pubmed/31710713
73 Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Sharman JL, Campo B, Cavanagh DR, Alexander SPH, Davenport AP, Spedding M, Davies JA; NC-IUPHAR. The IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY. Nucleic Acids Res. 2020 Jan 8;48(D1):D1006-D1021. doi: 10.1093/nar/gkz951. https://www.ncbi.nlm.nih.gov/pubmed/31691834
72 Southan C, Sharman JL, Faccenda E, Pawson AJ, Harding SD, Davies JA. Challenges of Connecting Chemistry to Pharmacology: Perspectives from Curating the IUPHAR/BPS Guide to PHARMACOLOGY. ACS Omega. 2018 Jul 31;3(7):8408-8420. doi: 10.1021/acsomega.8b00884. Review. https://www.ncbi.nlm.nih.gov/pubmed/30087946
71 Sharman JL, Harding SD, Southan C, Faccenda E, Pawson AJ, Davies JA; NC-IUPHAR. Accessing Expert-Curated Pharmacological Data in the IUPHAR/BPS Guide to PHARMACOLOGY. Curr Protoc Bioinformatics. 2018 Mar;61(1):1.34.1-1.34.46. doi: 10.1002/cpbi.46. https://www.ncbi.nlm.nih.gov/pubmed/30040201
70 Harding SD, Sharman JL, Faccenda E, Southan C, Pawson AJ, Ireland S, Gray AJG, Bruce L, Alexander SPH, Anderton S, Bryant C, Davenport AP, Doerig C, Fabbro D, Levi-Schaffer F, Spedding M, Davies JA; NC-IUPHAR. The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY. Nucleic Acids Res. 2018 Jan 4;46(D1):D1091-D1106. doi: 10.1093/nar/gkx1121. https://www.ncbi.nlm.nih.gov/pubmed/29149325
69 Alexander SP, Christopoulos A, Davenport AP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors. Br J Pharmacol. 2017 Dec;174 Suppl 1:S17-S129. doi: 10.1111/bph.13878. https://www.ncbi.nlm.nih.gov/pubmed/29055040
68 Alexander SP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Other ion channels. Br J Pharmacol. 2017 Dec;174 Suppl 1:S195-S207. doi: 10.1111/bph.13881. https://www.ncbi.nlm.nih.gov/pubmed/29055039
67 Alexander SP, Peters JA, Kelly E, Marrion NV, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Ligand-gated ion channels. Br J Pharmacol. 2017 Dec;174 Suppl 1:S130-S159. doi: 10.1111/bph.13879. https://www.ncbi.nlm.nih.gov/pubmed/29055038
66 Alexander SP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview. Br J Pharmacol. 2017 Dec;174 Suppl 1:S1-S16. doi: 10.1111/bph.13882. https://www.ncbi.nlm.nih.gov/pubmed/29055037
65 Alexander SP, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors. Br J Pharmacol. 2017 Dec;174 Suppl 1:S225-S271. doi: 10.1111/bph.13876. https://www.ncbi.nlm.nih.gov/pubmed/29055036
64 Alexander SP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters. Br J Pharmacol. 2017 Dec;174 Suppl 1:S360-S446. doi: 10.1111/bph.13883. https://www.ncbi.nlm.nih.gov/pubmed/29055035
63 Alexander SP, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes. Br J Pharmacol. 2017 Dec;174 Suppl 1:S272-S359. doi: 10.1111/bph.13877. https://www.ncbi.nlm.nih.gov/pubmed/29055034
62 Alexander SP, Striessnig J, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Voltage-gated ion channels. Br J Pharmacol. 2017 Dec;174 Suppl 1:S160-S194. doi: 10.1111/bph.13884. https://www.ncbi.nlm.nih.gov/pubmed/29055033
61 Alexander SP, Cidlowski JA, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Nuclear hormone receptors. Br J Pharmacol. 2017 Dec;174 Suppl 1:S208-S224. doi: 10.1111/bph.13880. https://www.ncbi.nlm.nih.gov/pubmed/29055032
60 Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: Transporters. Br J Pharmacol. 2015 Dec;172(24):6110-202. doi: 10.1111/bph.13355. https://www.ncbi.nlm.nih.gov/pubmed/26650446
59 Alexander SP, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: Enzymes. Br J Pharmacol. 2015 Dec;172(24):6024-109. doi: 10.1111/bph.13354. https://www.ncbi.nlm.nih.gov/pubmed/26650445
58 Alexander SP, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors. Br J Pharmacol. 2015 Dec;172(24):5979-6023. doi: 10.1111/bph.13353. https://www.ncbi.nlm.nih.gov/pubmed/26650444
57 Alexander SP, Cidlowski JA, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors. Br J Pharmacol. 2015 Dec;172(24):5956-78. doi: 10.1111/bph.13352. https://www.ncbi.nlm.nih.gov/pubmed/26650443
56 Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels. Br J Pharmacol. 2015 Dec;172(24):5942-55. doi: 10.1111/bph.13351. https://www.ncbi.nlm.nih.gov/pubmed/26650442
55 Alexander SP, Catterall WA, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels. Br J Pharmacol. 2015 Dec;172(24):5904-41. doi: 10.1111/bph.13349. https://www.ncbi.nlm.nih.gov/pubmed/26650441
54 Alexander SP, Peters JA, Kelly E, Marrion N, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: Ligand-gated ion channels. Br J Pharmacol. 2015 Dec;172(24):5870-903. doi: 10.1111/bph.13350. https://www.ncbi.nlm.nih.gov/pubmed/26650440
53 Alexander SP, Davenport AP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors. Br J Pharmacol. 2015 Dec;172(24):5744-869. doi: 10.1111/bph.13348. https://www.ncbi.nlm.nih.gov/pubmed/26650439
52 Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Buneman OP, Catterall WA, Cidlowski JA, Davenport AP, Fabbro D, Fan G, McGrath JC, Spedding M, Davies JA; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2015/16: Overview. Br J Pharmacol. 2015 Dec;172(24):5729-43. doi: 10.1111/bph.13347. https://www.ncbi.nlm.nih.gov/pubmed/26650438
51 Southan C, Sharman JL, Benson HE, Faccenda E, Pawson AJ, Alexander SP, Buneman OP, Davenport AP, McGrath JC, Peters JA, Spedding M, Catterall WA, Fabbro D, Davies JA; NC-IUPHAR. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucleic Acids Res. 2016 Jan 4;44(D1):D1054-68. doi: 10.1093/nar/gkv1037. Epub 2015 Oct 12. https://www.ncbi.nlm.nih.gov/pubmed/26464438
50 McGrath JC, Pawson AJ, Sharman JL, Alexander SP. BJP is linking its articles to the IUPHAR/BPS Guide to PHARMACOLOGY. Br J Pharmacol. 2015 Jun;172(12):2929-32. doi: 10.1111/bph.13112. Epub 2015 May 12. https://www.ncbi.nlm.nih.gov/pubmed/25965085
49 Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2013/14: enzymes. Br J Pharmacol. 2013 Dec;170(8):1797-867. doi: 10.1111/bph.12451. https://www.ncbi.nlm.nih.gov/pubmed/24528243
48 Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2013/14: transporters. Br J Pharmacol. 2013 Dec;170(8):1706-96. doi: 10.1111/bph.12450. https://www.ncbi.nlm.nih.gov/pubmed/24528242
47 Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors. Br J Pharmacol. 2013 Dec;170(8):1676-705. doi: 10.1111/bph.12449. https://www.ncbi.nlm.nih.gov/pubmed/24528241
46 Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors. Br J Pharmacol. 2013 Dec;170(8):1652-75. doi: 10.1111/bph.12448. https://www.ncbi.nlm.nih.gov/pubmed/24528240
45 Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2013/14: ion channels. Br J Pharmacol. 2013 Dec;170(8):1607-51. doi: 10.1111/bph.12447. https://www.ncbi.nlm.nih.gov/pubmed/24528239
44 Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels. Br J Pharmacol. 2013 Dec;170(8):1582-606. doi: 10.1111/bph.12446. https://www.ncbi.nlm.nih.gov/pubmed/24528238
43 Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators., Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, et al. The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444. https://www.ncbi.nlm.nih.gov/pubmed/24528237
42 Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators. The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors. Br J Pharmacol. 2013 Dec;170(8):1459-581. doi: 10.1111/bph.12445. https://www.ncbi.nlm.nih.gov/pubmed/24517644
41 Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, Davenport AP, McGrath JC, Peters JA, Southan C, Spedding M, Yu W, Harmar AJ; NC-IUPHAR. The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucleic Acids Res. 2014 Jan;42(Database issue):D1098-106. doi: 10.1093/nar/gkt1143. Epub 2013 Nov 14. https://www.ncbi.nlm.nih.gov/pubmed/24234439
40 Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. Print 2013 Jul. Review. https://www.ncbi.nlm.nih.gov/pubmed/23686350
39 Sharman JL, Benson HE, Pawson AJ, Lukito V, Mpamhanga CP, Bombail V, Davenport AP, Peters JA, Spedding M, Harmar AJ; NC-IUPHAR. IUPHAR-DB: updated database content and new features. Nucleic Acids Res. 2013 Jan;41(Database issue):D1083-8. doi: 10.1093/nar/gks960. Epub 2012 Oct 18. https://www.ncbi.nlm.nih.gov/pubmed/23087376
38 Alexander SP, Benson HE, Davenport A, Mathie A, McGrath IJ, Pawson AJ, Peters JA, Sharman JL, Spedding M, Harmar AJ. GuideToPharmacology.org--an update. Br J Pharmacol. 2012 Oct;167(4):697-8. doi: 10.1111/j.1476-5381.2012.02141.x. No abstract available. https://www.ncbi.nlm.nih.gov/pubmed/23003568
37 Ermakov A, Pells S, Freile P, Ganeva VV, Wildenhain J, Bradley M, Pawson A, Millar R, De Sousa PA. A role for intracellular calcium downstream of G-protein signaling in undifferentiated human embryonic stem cell culture. Stem Cell Res. 2012 Nov;9(3):171-84. doi: 10.1016/j.scr.2012.06.007. Epub 2012 Jul 5. https://www.ncbi.nlm.nih.gov/pubmed/22877821
36 Millar RP, Roseweir AK, Tello JA, Anderson RA, George JT, Morgan K, Pawson AJ. Kisspeptin antagonists: unraveling the role of kisspeptin in reproductive physiology. Brain Res. 2010 Dec 10;1364:81-9. doi: 10.1016/j.brainres.2010.09.044. Epub 2010 Sep 18. Review. https://www.ncbi.nlm.nih.gov/pubmed/20858467
35 Naidich M, Shterntal B, Furman R, Pawson AJ, Jabbour HN, Morgan K, Millar RP, Jia J, Tomic M, Stojilkovic S, Stern N, Naor Z. Elucidation of mechanisms of the reciprocal cross talk between gonadotropin-releasing hormone and prostaglandin receptors. Endocrinology. 2010 Jun;151(6):2700-12. doi: 10.1210/en.2009-1335. Epub 2010 Apr 14. https://www.ncbi.nlm.nih.gov/pubmed/20392830
34 Gardner S, Stavrou E, Rischitor PE, Faccenda E, Pawson AJ. Targeting mediators of Wnt signalling pathways by GnRH in gonadotropes. J Mol Endocrinol. 2010 Apr;44(4):195-201. doi: 10.1677/JME-09-0168. Epub 2010 Feb 4. Review. https://www.ncbi.nlm.nih.gov/pubmed/20133385
33 Ubuka T, Morgan K, Pawson AJ, Osugi T, Chowdhury VS, Minakata H, Tsutsui K, Millar RP, Bentley GE. Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. PLoS One. 2009 Dec 22;4(12):e8400. doi: 10.1371/journal.pone.0008400. https://www.ncbi.nlm.nih.gov/pubmed/20027225
32 Gardner S, Pawson AJ. Emerging targets of the GnRH receptor: novel interactions with Wnt signalling mediators. Neuroendocrinology. 2009;89(3):241-51. doi: 10.1159/000165377. Epub 2008 Oct 22. Review. https://www.ncbi.nlm.nih.gov/pubmed/18946197
31 Clarke IJ, Sari IP, Qi Y, Smith JT, Parkington HC, Ubuka T, Iqbal J, Li Q, Tilbrook A, Morgan K, Pawson AJ, Tsutsui K, Millar RP, Bentley GE. Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion. Endocrinology. 2008 Nov;149(11):5811-21. doi: 10.1210/en.2008-0575. Epub 2008 Jul 10. https://www.ncbi.nlm.nih.gov/pubmed/18617613
30 Lopez de Maturana R, Pawson AJ, Lu ZL, Davidson L, Maudsley S, Morgan K, Langdon SP, Millar RP. Gonadotropin-releasing hormone analog structural determinants of selectivity for inhibition of cell growth: support for the concept of ligand-induced selective signaling. Mol Endocrinol. 2008 Jul;22(7):1711-22. doi: 10.1210/me.2006-0537. Epub 2008 May 8. https://www.ncbi.nlm.nih.gov/pubmed/18467526
29 Pfleger KD, Pawson AJ, Millar RP. Changes to gonadotropin-releasing hormone (GnRH) receptor extracellular loops differentially affect GnRH analog binding and activation: evidence for distinct ligand-stabilized receptor conformations. Endocrinology. 2008 Jun;149(6):3118-29. doi: 10.1210/en.2008-0002. Epub 2008 Mar 20. https://www.ncbi.nlm.nih.gov/pubmed/18356273
28 Pawson AJ, Faccenda E, Maudsley S, Lu ZL, Naor Z, Millar RP. Mammalian type I gonadotropin-releasing hormone receptors undergo slow, constitutive, agonist-independent internalization. Endocrinology. 2008 Mar;149(3):1415-22. Epub 2007 Nov 26. https://www.ncbi.nlm.nih.gov/pubmed/18039780
27 Millar RP, Pawson AJ, Morgan K, Rissman EF, Lu ZL. Diversity of actions of GnRHs mediated by ligand-induced selective signaling. Front Neuroendocrinol. 2008 Jan;29(1):17-35. Epub 2007 Aug 23. Review. https://www.ncbi.nlm.nih.gov/pubmed/17976709
26 Lopez de Maturana R, Martin B, Millar RP, Brown P, Davidson L, Pawson AJ, Nicol MR, Mason JI, Barran P, Naor Z, Maudsley S. GnRH-mediated DAN production regulates the transcription of the GnRH receptor in gonadotrope cells. Neuromolecular Med. 2007;9(3):230-48. https://www.ncbi.nlm.nih.gov/pubmed/17914181
25 Gardner S, Maudsley S, Millar RP, Pawson AJ. Nuclear stabilization of beta-catenin and inactivation of glycogen synthase kinase-3beta by gonadotropin-releasing hormone: targeting Wnt signaling in the pituitary gonadotrope. Mol Endocrinol. 2007 Dec;21(12):3028-38. Epub 2007 Aug 23. https://www.ncbi.nlm.nih.gov/pubmed/17717075
24 Maudsley S, Naor Z, Bonfil D, Davidson L, Karali D, Pawson AJ, Larder R, Pope C, Nelson N, Millar RP, Brown P. Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit gene. Mol Endocrinol. 2007 May;21(5):1216-33. Epub 2007 Feb 27. https://www.ncbi.nlm.nih.gov/pubmed/17327421
23 Maudsley S, Davidson L, Pawson AJ, Freestone SH, Lopez de Maturana R, Thomson AA, Millar RP. Gonadotropin-releasing hormone functionally antagonizes testosterone activation of the human androgen receptor in prostate cells through focal adhesion complexes involving Hic-5. Neuroendocrinology. 2006;84(5):285-300. Epub 2007 Jan 4. https://www.ncbi.nlm.nih.gov/pubmed/17202804
22 Naor Z, Jabbour HN, Naidich M, Pawson AJ, Morgan K, Battersby S, Millar MR, Brown P, Millar RP. Reciprocal cross talk between gonadotropin-releasing hormone (GnRH) and prostaglandin receptors regulates GnRH receptor expression and differential gonadotropin secretion. Mol Endocrinol. 2007 Feb;21(2):524-37. Epub 2006 Nov 30. https://www.ncbi.nlm.nih.gov/pubmed/17138645
21 Morgan K, Sellar R, Pawson AJ, Lu ZL, Millar RP. Bovine and ovine gonadotropin-releasing hormone (GnRH)-II ligand precursors and type II GnRH receptor genes are functionally inactivated. Endocrinology. 2006 Nov;147(11):5041-51. Epub 2006 Aug 17. https://www.ncbi.nlm.nih.gov/pubmed/16916952
20 Dobkin-Bekman M, Naidich M, Pawson AJ, Millar RP, Seger R, Naor Z. Activation of mitogen-activated protein kinase (MAPK) by GnRH is cell-context dependent. Mol Cell Endocrinol. 2006 Jun 27;252(1-2):184-90. Epub 2006 May 8. Review. https://www.ncbi.nlm.nih.gov/pubmed/16682115
19 Barran PE, Roeske RW, Pawson AJ, Sellar R, Bowers MT, Morgan K, Lu ZL, Tsuda M, Kusakabe T, Millar RP. Evolution of constrained gonadotropin-releasing hormone ligand conformation and receptor selectivity. J Biol Chem. 2005 Nov 18;280(46):38569-75. Epub 2005 Sep 12. https://www.ncbi.nlm.nih.gov/pubmed/16157590
18 Pawson AJ, McNeilly AS. The pituitary effects of GnRH. Anim Reprod Sci. 2005 Aug;88(1-2):75-94. Review. https://www.ncbi.nlm.nih.gov/pubmed/15982836
17 Shacham S, Cheifetz MN, Fridkin M, Pawson AJ, Millar RP, Naor Z. Identification of Ser153 in ICL2 of the gonadotropin-releasing hormone (GnRH) receptor as a phosphorylation-independent site for inhibition of Gq coupling. J Biol Chem. 2005 Aug 12;280(32):28981-8. Epub 2005 Jun 17. https://www.ncbi.nlm.nih.gov/pubmed/15964850
16 Pawson AJ, Maudsley S, Morgan K, Davidson L, Naor Z, Millar RP. Inhibition of human type i gonadotropin-releasing hormone receptor (GnRHR) function by expression of a human type II GnRHR gene fragment. Endocrinology. 2005 Jun;146(6):2639-49. Epub 2005 Mar 10. https://www.ncbi.nlm.nih.gov/pubmed/15761034
15 Maudsley S, Davidson L, Pawson AJ, Chan R, Lopez de Maturana R, Millar RP. Gonadotropin-releasing hormone (GnRH) antagonists promote proapoptotic signaling in peripheral reproductive tumor cells by activating a Galphai-coupling state of the type I GnRH receptor. Cancer Res. 2004 Oct 15;64(20):7533-44. https://www.ncbi.nlm.nih.gov/pubmed/15492280
14 Millar RP, Pawson AJ. Outside-in and inside-out signaling: the new concept that selectivity of ligand binding at the gonadotropin-releasing hormone receptor is modulated by the intracellular environment. Endocrinology. 2004 Aug;145(8):3590-3. No abstract available. https://www.ncbi.nlm.nih.gov/pubmed/15265825
13 Ronacher K, Matsiliza N, Nkwanyana N, Pawson AJ, Adam T, Flanagan CA, Millar RP, Katz AA. Serine residues 338 and 339 in the carboxyl-terminal tail of the type II gonadotropin-releasing hormone receptor are critical for beta-arrestin-independent internalization. Endocrinology. 2004 Oct;145(10):4480-8. Epub 2004 Jun 17. https://www.ncbi.nlm.nih.gov/pubmed/15205374
12 Millar RP, Lu ZL, Pawson AJ, Flanagan CA, Morgan K, Maudsley SR. Gonadotropin-releasing hormone receptors. Endocr Rev. 2004 Apr;25(2):235-75. Review. https://www.ncbi.nlm.nih.gov/pubmed/15082521
11 Gault PM, Morgan K, Pawson AJ, Millar RP, Lincoln GA. Sheep exhibit novel variations in the organization of the mammalian type II gonadotropin-releasing hormone receptor gene. Endocrinology. 2004 May;145(5):2362-74. Epub 2004 Jan 28. https://www.ncbi.nlm.nih.gov/pubmed/14749360
10 Davidson L, Pawson AJ, Lopez de Maturana R, Freestone SH, Barran P, Millar RP, Maudsley S. Gonadotropin-releasing hormone-induced activation of diacylglycerol kinase-zeta and its association with active c-src. J Biol Chem. 2004 Mar 19;279(12):11906-16. Epub 2004 Jan 5. https://www.ncbi.nlm.nih.gov/pubmed/14707140
9 Davidson L, Pawson AJ, Millar RP, Maudsley S. Cytoskeletal reorganization dependence of signaling by the gonadotropin-releasing hormone receptor. J Biol Chem. 2004 Jan 16;279(3):1980-93. Epub 2003 Oct 14. https://www.ncbi.nlm.nih.gov/pubmed/14559894
8 Pawson AJ, Morgan K, Maudsley SR, Millar RP. Type II gonadotrophin-releasing hormone (GnRH-II) in reproductive biology. Reproduction. 2003 Sep;126(3):271-8. Review. https://www.ncbi.nlm.nih.gov/pubmed/12968935
7 Pawson AJ, Maudsley SR, Lopes J, Katz AA, Sun YM, Davidson JS, Millar RP. Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: a putative palmitoylation site and threonine doublet within the carboxyl-terminal tail Are critical. Endocrinology. 2003 Sep;144(9):3860-71. https://www.ncbi.nlm.nih.gov/pubmed/12933659
6 Morgan K, Conklin D, Pawson AJ, Sellar R, Ott TR, Millar RP. A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q.12. Endocrinology. 2003 Feb;144(2):423-36. https://www.ncbi.nlm.nih.gov/pubmed/12538601
5 Millar R, Lowe S, Conklin D, Pawson A, Maudsley S, Troskie B, Ott T, Millar M, Lincoln G, Sellar R, Faurholm B, Scobie G, Kuestner R, Terasawa E, Katz A. A novel mammalian receptor for the evolutionarily conserved type II GnRH. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9636-41. Epub 2001 Aug 7. https://www.ncbi.nlm.nih.gov/pubmed/11493674
4 Assefa D, Pawson AJ, McArdle CA, Millar RP, Flanagan CA, Roeske R, Davidson JS. A new photoreactive antagonist cross-links to the N-terminal domain of the gonadotropin-releasing hormone receptor. Mol Cell Endocrinol. 1999 Oct 25;156(1-2):179-88. https://www.ncbi.nlm.nih.gov/pubmed/10612436
3 Myburgh DB, Pawson AJ, Davidson JS, Flanagan CA, Millar RP, Hapgood JP. A single amino acid substitution in transmembrane helix VI results in overexpression of the human GnRH receptor. Eur J Endocrinol. 1998 Oct;139(4):438-47. https://www.ncbi.nlm.nih.gov/pubmed/9820623
2 Pawson AJ, Katz A, Sun YM, Lopes J, Illing N, Millar RP, Davidson JS. Contrasting internalization kinetics of human and chicken gonadotropin-releasing hormone receptors mediated by C-terminal tail. J Endocrinol. 1998 Mar;156(3):R9-12. https://www.ncbi.nlm.nih.gov/pubmed/9582516
1 Davidson JS, Assefa D, Pawson A, Davies P, Hapgood J, Becker I, Flanagan C, Roeske R, Millar R. Irreversible activation of the gonadotropin-releasing hormone receptor by photoaffinity cross-linking: localization of attachment site to Cys residue in N-terminal segment. Biochemistry. 1997 Oct 21;36(42):12881-9. https://www.ncbi.nlm.nih.gov/pubmed/9335546